The Case of the Missing Chromosomes
Our story starts with cells. Not our cells but the cells of our closest relatives. The great apes. Within the nucleus of their cells the great apes have 24 chromosome pairs. We have 23 pairs. If we share a common ancestor, what happened to the missing chromosomes?
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Works Cited
Biribissi Biribissi. “Sherlock , Spock: However Improbable.” YouTube, 17 Feb. 2016, www.youtube.com/watch?v=2mMPJi-5z14.
Dreszer, Timothy, et al. “Biased Clustered Substitutions in the Human Genome: The Footprints of Male-driven Biased Gene Conversion.” Genome Research, vol. 17, no. 10, Cold Spring Harbor Laboratory Press, Sept. 2007, pp. 1420–30. https://doi.org/10.1101/gr.6395807.
Evolution: Library: Human Chromosome 2. www.pbs.org/wgbh/evolution/library/07/3/l_073_47.html.
Fan, Yuxin, et al. “Genomic Structure and Evolution of the Ancestral Chromosome Fusion Site in 2q13–2q14.1 and Paralogous Regions on Other Human Chromosomes.” Genome Research, vol. 12, no. 11, Cold Spring Harbor Laboratory Press, Nov. 2002, pp. 1651–62. https://doi.org/10.1101/gr.337602.
Hillier, La Deana W., et al. “Generation and Annotation of the DNA Sequences of Human Chromosomes 2 and 4.” Nature, vol. 434, no. 7034, Nature Portfolio, Apr. 2005, pp. 724–31. https://doi.org/10.1038/nature03466.
Poszewiecka, Barbara, et al. “Revised Time Estimation of the Ancestral Human Chromosome 2 Fusion.” BMC Genomics, vol. 23, no. S6, Springer Science+Business Media, Aug. 2022, https://doi.org/10.1186/s12864-022-08828-7.
“Scientists Analyze Chromosomes 2 and 4.” Genome.gov, www.genome.gov/13514624/2005-release-scientists-analyze-chromosomes-2-and-4.
Music in this Episode
Firefly by Podington Bear, License (CC BY 3.0): Artist website: soundofpicture.com
Crusty Lily by Podington Bear, License (CC BY 3.0): Artist website: soundofpicture.com
Horn Haze by Podington Bear, License (CC BY 3.0): Artist website: soundofpicture.com
Poof by Podington Bear, License (CC BY 3.0): Artist website: soundofpicture.com Genetic Engineering & Biotechnology news
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